Today's Challenges. Tomorrow's Solutions.

Strategic Solutions for Hematology + Oncology That Protect Drug & Service Value

Oncology economics live in the drug. Fulcrum Health Partners advises practices, oncology CFOs, and PE-backed platforms across buy-and-bill margin, ASP+ methodology, medical-versus-pharmacy benefit strategy, white/brown bagging, pathways, and 340B — turning the most complex reimbursement in medicine into durable enterprise value.

$2.7B
Reimbursement Opportunity Identified
12,500+
Payer Contracts Reviewed
50
States Served
350+
Client Engagements
The Oncology Reimbursement Landscape

The thinnest margin in medicine, on the highest-cost drugs

In oncology, the drug is the business — and the spread that funds the practice is razor-thin.

Medicare pays physician-administered drugs at ASP + 6% — roughly 4.3% after the sequester — while a two-quarter ASP lag can leave practices "underwater," reimbursed below their acquisition cost when prices rise. Every dollar of buy-and-bill margin is under pressure.

Payers are pushing drugs from the medical benefit to the pharmacy benefit, mandating white and brown bagging, steering infusion by site of care, and tightening pathways and prior authorization. Layered over 340B dynamics and value-based models like the EOM, the result is the most complex reimbursement environment in healthcare — and precisely where Fulcrum works.

Figures reflect current CMS/MedPAC methodology and industry sources, 2024–2026.

Buy-and-Bill Spread — Illustrative

Where the margin lives on a physician-administered drug
Net acquisition Drug cost ASP + ~4.3% Reimbursement spread

The entire practice runs on the thin brass band. Bagging mandates, benefit shifts, and ASP lag all threaten it.

ASP+6%
Medicare Part B drug add-on
~4.3%
Effective add-on after 2% sequester
2Q
ASP pricing lag that can leave drugs underwater
2030
Enhancing Oncology Model (EOM) runs through
Reimbursement Intelligence in Action

Payer mix and buy-and-bill economics, by profile

Fulcrum turns your claims and drug data into executive dashboards. Select an oncology profile to explore a sample payer-mix and drug-margin view.

Community Oncology · Payer Mix & Drug Economics Live Sample
Payer Mix (by charges)
Net Payments & Buy-and-Bill Drug Margin by Payer
Net payments (service + drug)Buy-and-bill drug margin

Illustrative sample dashboard. Fulcrum builds these from your practice-management, dispensing, and claims data by J-code and regimen.

Our Oncology Advisory Solutions

Advisory organized around the economics you manage

Not a service menu — the drug and service reimbursement problems that decide oncology profitability, and the strategy, analytics, and negotiation capabilities that resolve them.

01 The Challenge — Buy-and-bill margin under constant pressure

Drug & Buy-and-Bill Reimbursement Strategy

The spread that funds the practice is thin and eroding. We optimize ASP+ capture, identify underwater drugs, and defend buy-and-bill economics across every payer and regimen.

ASP+ methodology optimization
Underwater-drug identification
Buy-and-bill margin protection
J-code / HCPCS accuracy
Drug waste (JW/JZ) capture
Inventory & ASP-lag strategy
Regimen-level margin analysis
GPO & acquisition benchmarking
Biosimilar strategy
02 The Challenge — Payers moving drugs off the medical benefit

Medical vs. Pharmacy Benefit & Bagging Defense

Benefit shifts and white/brown bagging mandates strip margin and disrupt care. We build the strategy and payer response to protect it.

Medical-benefit defense
White/brown bagging response
Specialty pharmacy strategy
Payer policy negotiation
Safety & workflow positioning
Site-of-care strategy
03 The Challenge — Commercial drug & service rates that lag

Commercial Payer Strategy & Contracting

Commercial oncology hinges on AWP/WAC-based drug terms and administration rates. We negotiate both — with the data to back it.

AWP / WAC-based drug rates
Administration & E&M rates
Drug carve-out terms
Multi-payer strategy
Escalators & renewals
Contract compliance
04 The Challenge — You can't manage margin you can't see

Oncology Reimbursement Analytics

Drug- and regimen-level modeling that shows exactly where margin is made and lost, by payer and J-code.

Drug-level margin modeling
ASP-lag & underwater analysis
Payment variance analysis
Commercial rate benchmarking
Denial & prior-auth trends
Executive dashboards
05 The Challenge — Earned revenue that never arrives

Revenue Integrity & Contract Compliance

We ensure contractual and drug-payment entitlement becomes realized revenue — surfacing underpayments and leakage.

Drug underpayment identification
Contract compliance audits
Waste-modifier verification
Prior-auth & denial recovery
Payment variance reviews
Revenue leakage identification
06 The Challenge — Growth and platform economics

Platform, Growth & Transaction Advisory

For PE-backed and multisite platforms, we bring institutional-grade reimbursement to diligence, integration, and expansion.

Platform reimbursement assessment
M&A drug-margin diligence
Contract harmonization
Infusion & site expansion
Value-based care & EOM
Enterprise value creation
The Forces Reshaping Oncology Economics

The strategic questions every oncology leader now faces

Beyond the fee schedule, these are the dynamics that decide oncology margin — and where Fulcrum builds the strategy.

01

Medical vs. Pharmacy Benefit Strategy

Defending medical-benefit buy-and-bill as payers push drugs to the PBM-controlled pharmacy benefit.

02

White & Brown Bagging

Responding to bagging mandates that eliminate buy-and-bill margin and raise safety and workflow risk.

03

Site-of-Care & Infusion Steerage

Payer programs steering infusion by site of care — and the medical-benefit drug-management vendors enforcing them.

04

Oncology Pathways & Prior Auth

Navigating pathway programs and utilization management that constrain regimen choice and add burden.

05

340B Interplay

Understanding the 340B advantage for hospitals and its competitive pressure on independent practices.

06

Value-Based Care & the EOM

Positioning for the Enhancing Oncology Model and value-based arrangements running through 2030.

Buy-and-Bill Margin Calculator

See what optimized drug reimbursement is worth

Model the annual margin recovery from moving your net drug reimbursement toward its optimized level across Medicare and commercial payers.

Your inputs

Enter approximate figures — nothing is stored or transmitted.

$
%
Estimated annual drug margin recovery
$0
Adjust the inputs to model your opportunity.
$0
Per $1M of drug spend
$0
3-year cumulative

Directional estimate for discussion only; Medicare Part B margin is capped at statutory ASP+6%. Commercial optimization varies by contract. A Fulcrum analysis models your actual drug book and payer terms.

Why Oncology Leaders Choose Fulcrum

The advisor that speaks oncology's economic language

Independent by design and fluent in buy-and-bill — ASP+, AWP/WAC, benefit design, bagging, pathways, and 340B — delivered by the people who do the work.

Independent Advisor

No networks, no downstream fees — only your economics.

Buy-and-Bill & ASP+ Expertise

Deep fluency in the economics that fund the practice.

Benefit & Bagging Strategy

Medical-vs-pharmacy strategy and bagging defense.

Drug-Level Analytics

Margin modeling down to the J-code and regimen.

National Payer Experience

Insight into payer drug policy in every market.

PE & Platform Experience

Platform-grade reimbursement from diligence to exit.

Healthcare Economics

Quantified analysis behind every recommendation.

Data-Driven Support

Dashboards and intelligence that clarify the path.

Client Outcomes

How Fulcrum helps — and what it's worth

Anonymized outcomes from Fulcrum engagements with hematology & oncology practices and platforms.

Community Oncology
$3.1M
drug margin recovered

Identified underwater drugs and ASP+ capture gaps across the regimen book — recovered and protected going forward.

Multisite Hem/Onc
Buy-and-bill preserved
bagging mandate defeated

Built the payer strategy and clinical case that reversed a white-bagging mandate — preserving margin and continuity of care.

PE-Backed Platform
8 pts
commercial uplift

Improved commercial drug and administration reimbursement across a multi-state oncology platform.

Fulcrum Intelligence

Oncology insights & analysis

Executive briefings on the forces moving oncology economics — buy-and-bill margin, benefit design, bagging, pathways, and 340B.

Explore Oncology Insights
Today's Challenges. Tomorrow's Solutions.

Let's Optimize Your Drug & Service Reimbursement.

Whether you're defending buy-and-bill margin, responding to a bagging mandate, negotiating commercial drug and administration rates, or building a platform, Fulcrum Health Partners delivers the reimbursement expertise oncology leaders rely on.